http://coloncancersupport.colonclub.com/viewtopic.php?f=1&t=10476

Your body truly hates chemo. After my first round of FOLFOX my blood counts were in the toilet – so I had to postpone round #2 an extra week. After that my oncologist always gave me the Neulasta (sp?) shot – it was just one shot and they gave it to me on day #3 – the day they disconnected my pump. If they remembered to bring the shot up to room temp or at least close, it didn’t hurt as much going in. And I was one of the rare exceptions that did NOT have any bone pain. My shoulders and neck would get a little stiff/sore, but not bad. My big thing was nausea – I experienced other side effects, usually the first day – like the eye twitching, muscles locking up – but nothing like what you’re going through. And the Emend made the nausea bearable. Not good – but I could suck it up – be tough – and get through it. When I thought I just couldn’t go on, a break would come up for some reason or another – like the 3 week break before and after radiation.